Photochemical Properties of Water-soluble Fluorinated Zinc Phthalocyanines and their Photocytotoxicity Against HeLa Cells

Author(s):  
KAORU FUKUSHIMA ◽  
KENJI TABATA ◽  
ICHIRO OKURA

Three types of amphiphilic water-soluble fluorinated zinc phthalocyanines are characterized. They have absorption bands at long wavelength, which cause greater penetration depth of a tissue. The uptake and photodynamic activity of the phthalocyanines against HeLa cells were measured, showing that the phthalocyanines exhibited higher photodynamic activities than zinc tetrasulfonated phthalocyanine.

2016 ◽  
Vol 4 (32) ◽  
pp. 5331-5348 ◽  
Author(s):  
Shuailiang Wang ◽  
Anyao Bi ◽  
Wenbin Zeng ◽  
Zhen Cheng

Upconversion nanoparticles (UCNPs) are able to convert long wavelength excitation light into high energy ultraviolet (UV) or visible emissions, and they have attracted significant attention because of their distinct photochemical properties including sharp emission bands, low autofluorescence, high tissue penetration depth and minimal photodamage to tissues.


2009 ◽  
Vol 159 (15-16) ◽  
pp. 1563-1571 ◽  
Author(s):  
Mahmut Durmuş ◽  
Zekeriya Bıyıklıoğlu ◽  
Halit Kantekin

1991 ◽  
Vol 127 (1) ◽  
pp. 24 ◽  
Author(s):  
Alessandra Andreoni ◽  
Alberto Colasanti ◽  
Vincenzo Malatesta ◽  
Giuseppe Roberti

2017 ◽  
Vol 1 (1) ◽  
pp. 371-383 ◽  
Author(s):  
Joicy Selvaraj ◽  
Arun Mahesh ◽  
Vijayshankar Asokan ◽  
Vaseeharan Baskaralingam ◽  
Arunkumar Dhayalan ◽  
...  
Keyword(s):  

1940 ◽  
Vol 23 (4) ◽  
pp. 483-494 ◽  
Author(s):  
C. S. French

Absorption curves have been obtained in the spectral region of 450 to 900 mµ for the water soluble cell juice of four species of photosynthetic bacteria, Spirillum rubrum (strain S1), Rhodovibrio sp. (strain Gaffron), Phaeomonas sp. (strain Delft), and Streptococcus varians (strains C11 and orig.). These curves all show maxima at 790 and 590 mµ due to bacteriochlorophyll, whose highest band, however, occurs at 875, 855, or 840 mµ depending on the species. The bacteria that appear red rather than brown have a band at 550 mµ due to a carotinoid pigment. An absolute absorption curve of bacteriophaeophytin has maxima at 530 and 750 mµ. The extraction of cell juice by supersonic vibration does not change the position of the absorption bands or of the light absorbing capacity of the pigment.


Materials ◽  
2020 ◽  
Vol 13 (9) ◽  
pp. 2083
Author(s):  
Tiago D. Martins ◽  
Eurico Lima ◽  
Renato E. Boto ◽  
Diana Ferreira ◽  
José R. Fernandes ◽  
...  

Photodynamic therapy is a medical modality developed for the treatment of several diseases of oncological and non-oncological etiology that requires the presence of a photosensitizer, light and molecular oxygen, which combined will trigger physicochemical reactions responsible for reactive oxygen species production. Given the scarcity of photosensitizers that exhibit desirable characteristics for its potential application in this therapeutic strategy, the main aims of this work were the study of the photophysical and photochemical properties and the photobiological activity of several dicyanomethylene squaraine cyanine dyes. Thus, herein, the study of their aggregation character, photobleaching and singlet oxygen production ability, and the further application of the previously synthesized dyes in Caco-2 and HepG2 cancer cell lines, to evaluate their phototherapeutic effects, are described. Dicyanomethylene squaraine dyes exhibited moderate light-stability and, despite the low singlet oxygen quantum yields, were a core of dyes that exhibited relevant in vitro photodynamic activity, as there was an evident increase in the toxicity of some of the tested dyes exclusive to radiation treatments.


2012 ◽  
Vol 11 (4) ◽  
pp. 679 ◽  
Author(s):  
Zafar Iqbal ◽  
Nkosiphile Masilela ◽  
Tebello Nyokong ◽  
Alexey Lyubimtsev ◽  
Michael Hanack ◽  
...  

2003 ◽  
Vol 155 (1-3) ◽  
pp. 127-131 ◽  
Author(s):  
Petr Zimcik ◽  
Miroslav Miletin ◽  
Jan Ponec ◽  
Miroslav Kostka ◽  
Zdenek Fiedler

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